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Our top choices for South Central Houston hotels

1. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.6 out of 10, Excellent, (2,253 reviews)
The price is CA $118
CA $139 total
includes taxes & fees
Nov 22 - Nov 23

2. Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
9.2 out of 10, Wonderful, (279 reviews)
The price is CA $129
CA $151 total
includes taxes & fees
Nov 10 - Nov 11

3. 2820 Blodgett St
2820 Blodgett StSouth Central Houston
The price is CA $127
CA $149 total
includes taxes & fees
Nov 10 - Nov 11

4. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,285 reviews)
The price is CA $204
CA $254 total
includes taxes & fees
Nov 15 - Nov 16

5. InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.4 out of 10, Exceptional, (1,009 reviews)
The price is CA $215
CA $280 total
includes taxes & fees
Nov 22 - Nov 23

6. DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very good, (722 reviews)
The price is CA $161
CA $188 total
includes taxes & fees
Nov 22 - Nov 23

7. Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,004 reviews)
The price is CA $215
CA $297 total
includes taxes & fees
Nov 22 - Nov 23

8. Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.2 out of 10, Wonderful, (102 reviews)
The price is CA $211
CA $288 total
includes taxes & fees
Nov 30 - Dec 1

9. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,012 reviews)
The price is CA $273
CA $386 total
includes taxes & fees
Nov 22 - Nov 23

10. 2824 Aeon Living
2824 Aeon LivingSouth Central Houston
The price is CA $172
CA $201 total
includes taxes & fees
Nov 12 - Nov 13

11. Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (998 reviews)
The price is CA $207
CA $243 total
includes taxes & fees
Nov 23 - Nov 24

12. Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very good, (1,000 reviews)
The price is CA $129
CA $151 total
includes taxes & fees
Nov 22 - Nov 23

13. La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (609 reviews)
The price is CA $245
CA $287 total
includes taxes & fees
Nov 19 - Nov 20

14. Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.8 out of 10, Exceptional, (83 reviews)
The price is CA $185
CA $217 total
includes taxes & fees
Nov 10 - Nov 11

15. Scott Inn Suites - Downtown Houston
Scott Inn Suites - Downtown HoustonSouth Central Houston
8.4 out of 10, Very good, (49 reviews)
The price is CA $91
CA $106 total
includes taxes & fees
Dec 10 - Dec 11

16. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (221 reviews)
The price is CA $292
CA $363 total
includes taxes & fees
Nov 10 - Nov 11

17. Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.8 out of 10, (245 reviews)
The price is CA $83
CA $97 total
includes taxes & fees
Nov 15 - Nov 16

18. Fifa Stay 2BR Near NRG DT Med Center -3
Fifa Stay 2BR Near NRG DT Med Center -3South Central Houston
The price is CA $231
CA $270 total
includes taxes & fees
Nov 12 - Nov 13

19. Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
6.2 out of 10, (1,003 reviews)
The price is CA $95
CA $112 total
includes taxes & fees
Dec 6 - Dec 7

20. Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very good, (220 reviews)
The price is CA $97
CA $114 total
includes taxes & fees
Nov 10 - Nov 11
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in South Central Houston
![]() Hilton Houston Plaza/Medical CenterSouth Central Houston | ![]() Downtowner Inns - Houston DowntownSouth Central Houston | ![]() The Westin Houston Medical Center/Museum DistrictSouth Central Houston | ![]() InterContinental Houston by IHGSouth Central Houston | ![]() DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston |
|---|---|---|---|---|
8.6 Excellent 2,253 reviews | 9.2 Wonderful 279 reviews | 9.2 Wonderful 1,285 reviews | 9.4 Exceptional 1,009 reviews | 8.4 Very good 722 reviews |
The price is CA $118 CA $139 total includes taxes & fees Nov 22 - Nov 23 | The price is CA $129 CA $151 total includes taxes & fees Nov 10 - Nov 11 | The price is CA $204 CA $254 total includes taxes & fees Nov 15 - Nov 16 | The price is CA $215 CA $280 total includes taxes & fees Nov 22 - Nov 23 | The price is CA $161 CA $188 total includes taxes & fees Nov 22 - Nov 23 |
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Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.



















































































